abstract：BACKGROUND:Medical robot is a promising surgical tool, but no specific one has been designed for interventional treatment of chronic pain. We developed a computed tomography-image based navigation robot using a new registration method with binocular vision. This kind of robot is appropriate for minimal invasive interve...

journal_title：World journal of clinical cases

authors： Wang R,Han Y,Luo MZ,Wang NK,Sun WW,Wang SC,Zhang HD,Lu LJ

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Extrahepatic metastasis (EHM) from hepatocellular carcinoma (HCC) occurs in 10%-15% of cases following initial treatment. The most frequent sites of EHM are the lung, lymph nodes, and bone. Gastrointestinal or brain metastasis from HCC is rarely reported. Here, we report a rare case of concurrent HCC metasta...

journal_title：World journal of clinical cases

authors： Kim R,Song J,Kim SB

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Coronary artery spasm is a major cause of myocardial ischemia. Although coronary artery spasm has been known for a long time, its mechanism has not yet been identified. Many clinicians, especially young clinicians pay less attention to coronary artery spasm, which may lead to some patients not being appropri...

journal_title：World journal of clinical cases

authors： Wu HY,Cao YW,Chang FJ,Liang L

更新日期：2020-08-26 00:00:00

abstract：:The current pandemic of coronavirus disease 2019 (COVID-19) which was first detected in Wuhan, China in December 2019 is caused by the novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The virus has quickly spread to a large number of countries leading to a great number of deaths. U...

journal_title：World journal of clinical cases

authors： AlNaamani K,AlSinani S,Barkun AN

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Dydrogesterone has shown significant efficacy in treatment of irregular menstrual cycle due to abnormal uterine bleeding - ovulation dysfunction (AUB-O), but there were few relevant studies. This observational study was designed to evaluate the effectiveness of dydrogesterone for the treatment of Chinese pat...

journal_title：World journal of clinical cases

authors： Wang L,Guan HY,Xia HX,Chen XY,Zhang W

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Type A insulin resistance syndrome is a rare disorder caused by mutations in the gene encoding the insulin receptor. Its coexistence with ovarian serous papillary cystadenofibroma is even rarer. CASE SUMMARY:A 14-year-old girl developed type A insulin resistance syndrome and showed high fasting insulin, glu...

journal_title：World journal of clinical cases

authors： Yan FF,Huang BK,Chen YL,Zhuang YZ,You XY,Liu CQ,Li XJ

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) is a valuable therapeutic technique for pancreatobiliary diseases, and its application in the elderly is no longer limited. However, a higher incidence of procedure difficulty and periprocedural adverse events might be expected in elderly patients due to ...

journal_title：World journal of clinical cases

authors： Tabak F,Wang HS,Li QP,Ge XX,Wang F,Ji GZ,Miao L

更新日期：2020-07-26 00:00:00

abstract：BACKGROUND:Pulmonary benign metastatic leiomyoma (PBML), which is very rare, is a type of benign metastatic leiomyoma (BML). Here, we report a case of PBML, finally diagnosed through multidisciplinary team (MDT) discussions, and provide a literature review of the disease. CASE SUMMARY:A 55-year old asymptomatic woman ...

journal_title：World journal of clinical cases

authors： Dai HY,Guo SL,Shen J,Yang L

更新日期：2020-07-26 00:00:00

abstract：:Chronic thromboembolic pulmonary hypertension (CTEPH) is a complex chronic disease in which pulmonary artery stenosis or obstruction caused by organized thrombus can lead to increased pulmonary artery pressure and pulmonary vascular resistance, ultimately triggering progressive right heart failure and death. Currently...

journal_title：World journal of clinical cases

authors： Jin Q,Zhao ZH,Luo Q,Zhao Q,Yan L,Zhang Y,Li X,Yang T,Zeng QX,Xiong CM,Liu ZH

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:Emergency department (ED) overcrowding is a severe health care concern, while anxiety and depression rates among ED patients have been reported to be substantially higher compared to the general population. We hypothesized that anxiety due to over crowdedness may lead to adverse events in EDs. AIM:To invest...

journal_title：World journal of clinical cases

authors： Wang S,Gao JY,Li X,Wu Y,Huo XX,Han CX,Kang MJ,Sun H,Ge BL,Liu Y,Liu YQ,Zhou JP,Wang Z

更新日期：2020-07-06 00:00:00

abstract：:Gastrointestinal (GI) cancer is one of the leading causes of cancer-related deaths worldwide. According to the Global Cancer Statistics, colorectal cancer is the second leading cause of cancer-related mortality, closely followed by gastric cancer (GC). Environmental, dietary, and lifestyle factors including cigarette ...

journal_title：World journal of clinical cases

authors： Wang LY,Zhao S,Lv GJ,Ma XJ,Zhang JB

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Previous publications indicated that genetic predisposition might play important roles in the onset of osteonecrosis of the femoral head (ONFH) in systemic lupus erythematosus (SLE). Some gene loci such as complement C3d receptor 2 (CR2), nitric oxide synthase 3 (NOS3), collagen type II alpha 1 chain (COL2A1...

journal_title：World journal of clinical cases

authors： Sun HS,Yang QR,Bai YY,Hu NW,Liu DX,Qin CY

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP), a subtype of thrombotic microangiopathy, has a very high fatality rate if there is no timely diagnosis or treatment. Here, we report a case of TTP refractory to high displacement plasma exchange, which was later successfully treated with rituximab. CASE SUMMARY:Her...

journal_title：World journal of clinical cases

authors： Chen J,Jin JX,Xu XF,Zhang XX,Ye XN,Huang J

更新日期：2020-06-26 00:00:00

abstract：:In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastas...

journal_title：World journal of clinical cases

authors： Wang Q,Yu CR

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Postoperative unobstructed drainage is an important measure for avoiding hematoma formation and preventing complications from anterior cervical surgery. AIM:To discuss the characteristics and key points of clinical management of two types of commonly used negative pressure drainage systems in clinical setti...

journal_title：World journal of clinical cases

authors： Su QH,Zhu K,Li YC,Chen T,Zhang Y,Tan J,Guo S

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:Waldenström macroglobulinemia (WM) is a type of small lymphocytic lymphoma that mainly affects the bone marrow, spleen, and lymph nodes. A subset of patients with WM demonstrates extramedullary involvement (4.4%), and the most frequent extramedullary disease site involved is the lungs (30%). CASE SUMMARY:A ...

journal_title：World journal of clinical cases

authors： Zhao DF,Ning HY,Cen J,Liu Y,Qian LR,Han ZH,Shen JL

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:In rare cases, odontogenic keratocysts (ODs) transform into squamous cell carcinoma. Intervals between the first attendance of a patient and the diagnosis of OD with malignant transformation vary from weeks to years. In this article, we report a case of malignancy derived from OD with a five-day delay in dia...

journal_title：World journal of clinical cases

authors： Luo XJ,Cheng ML,Huang CM,Zhao XP

更新日期：2020-06-06 00:00:00

abstract：:Hematopoietic stem cell transplantation has become a curative choice of many hematopoietic malignancy, but graft-vs-host disease (GVHD) has limited the survival quality and overall survival of hematopoietic stem cell transplantation. Understanding of the immune cells' reaction in pathophysiology of GVHD has improved, ...

journal_title：World journal of clinical cases

authors： Hong YQ,Wan B,Li XF

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:This study aimed to identify factors associated with antibiotic-associated diarrhea (AAD) in patients in the department of intensive care medicine who received antibiotic monotherapy in order to reduce the incidence of AAD and improve rational use of antibiotics in these patients. AIM:To report the incidenc...

journal_title：World journal of clinical cases

authors： Zhou H,Xu Q,Liu Y,Guo LT

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:Heterotopic pancreas is a common lesion found in the gastrointestinal tract and is usually considered a benign disease. Reports of malignant change of heterotopic pancreas are scarce. CASE SUMMARY:A 44-year-old Chinese female underwent a gastroscopy to assess abdominal distension that had persisted for 2 mo...

journal_title：World journal of clinical cases

authors： Xiong Y,Xie Y,Jin DD,Wang XY

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:A vascular tumor is a benign tumor with unique clinical and pathological features. Perirenal vascular tumor is extremely rare and has not yet been reported. Clinically, it manifests as soreness and swelling. Color ultrasound and renal angiography illustrated the perirenal mass, which was closely connected wi...

journal_title：World journal of clinical cases

authors： Zhang C,Fu B,Xu S,Zhou XC,Cheng XF,Fu WQ,Wang GX

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:High-riding nipple is one of the common complications after mastopexty and breast reconstruction. However, to date, a limited number of techniques have concentrated on how to lower the high-riding nipple with enlarged areola. CASE SUMMARY:This is a case report describing a combination of surgical techniques...

journal_title：World journal of clinical cases

authors： Qin F,Yu NZ,Yang E,Zeng A,Hao Y,Zhu L,Wang XJ

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:The most important factors affecting the decision of organ donation are socioeconomic, educational, cultural, and religious factors. AIM:To evaluate Islamic religious officials' attitudes and behaviors toward and level of knowledge on organ donation and transplantation. METHODS:This study surveyed 2350 Isl...

journal_title：World journal of clinical cases

authors： Akbulut S,Ozer A,Firinci B,Saritas H,Demyati K,Yilmaz S

更新日期：2020-05-06 00:00:00

abstract：:Probiotics are known as "live microorganisms" and have been proven to have a health effect on hosts at the proper dose. Recently, a kind of probiotic mixture including eight live bacterial strains, VSL#3, has attracted considerable attention for its combined effect. VSL#3 is the only probiotic considered as a kind of ...

journal_title：World journal of clinical cases

authors： Cheng FS,Pan D,Chang B,Jiang M,Sang LX

更新日期：2020-04-26 00:00:00

abstract：BACKGROUND:Familial cases of autosomal recessive spastic ataxia of charlevoix-saguenay have not been reported in the Arabian Peninsula, although the consanguineous marriage rate is very high. We report the first family from the Arabian Peninsula harboring a novel frameshift mutation in the SACS gene. CASE SUMMARY:A 33...

journal_title：World journal of clinical cases

authors： Al-Ajmi A,Shamsah S,Janicijevic A,Williams M,Al-Mulla F

更新日期：2020-04-26 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) is a major public health emergency with obvious characteristics of human-to-human transmission, and there are infective asymptomatic carriers. Early identification and proper management of patients with COVID-19 are important. Features in chest computed tomography (CT) can...

journal_title：World journal of clinical cases

authors： Chen LR,Chen ZX,Liu YC,Peng L,Zhang Y,Xu Q,Lin Q,Tao YM,Wu H,Yin S,Hu YJ

更新日期：2020-04-26 00:00:00

abstract：BACKGROUND:Lymphoepithelioma-like carcinoma (LELC) is a non-keratinizing carcinoma with rich lymphocytic infiltration, which primarily originates from the nasopharynx. Primary lung LELC is a type of lung cancer with a relatively low incidence. Herein, we report a rare case of lung LELC with expression of CD56. We also ...

journal_title：World journal of clinical cases

authors： Yang L,Liang H,Liu L,Guo L,Ying JM,Shi SS,Hu XS

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Apatinib is a small-molecule multitargeted tyrosine kinase inhibitor. Apatinib has demonstrated encouraging antitumor activities. This study aimed to observe the efficacy and safety of apatinib for the treatment of multiple brain micrometastases. CASE SUMMARY:We report two patients with multiple brain micro...

journal_title：World journal of clinical cases

authors： Guo JH,Wang YY,Zhang JW,Liu PM,Hao YJ,Duan HR

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Solitary respiratory papilloma is a rare epithelial tumor that can be categorized into multiple subtypes depending on tumor location, histological presentation and number. The glandular type is the rarest, with only 30 cases available within the field. Hence, information on its identification and treatment i...

journal_title：World journal of clinical cases

authors： Wu CW,Chen A,Huang TW

更新日期：2020-03-26 00:00:00

abstract：BACKGROUND:Giant paraesophageal hiatal hernias (HH) are very infrequent, and their spectrum of clinical manifestations is large. Giant HH mainly occurs in elderly patients, and its relationship with anemia has been reported. For the surgical treatment of large HH, Nissen fundoplication is the most common antireflux pro...

journal_title：World journal of clinical cases

authors： Yasheng D,Wulamu W,Li YL,Tuhongjiang A,Abudureyimu K

更新日期：2020-03-26 00:00:00

abstract：BACKGROUND:Generally, hemangiomas do not require surgical intervention; however, cases of large hemangiomas, potentially involving the throat and trachea, necessitate surgical therapy. Here, we present a case of hypopharyngeal hemangioma in an adult that was successfully treated with neodymium-doped yttrium aluminum ga...

journal_title：World journal of clinical cases

authors： Jin M,Wang CY,Da YX,Zhu W,Jiang H

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Gastric signet ring cell carcinoma (GSRCC) is one of the most malignant tumors. It has the features of high invasiveness, rapid progression, and resistance to chemotherapy. However, systematic analyses of mRNAs have not yet been performed for GSRCC. AIM:To identify key mRNAs and signaling pathways in GSRCC....

journal_title：World journal of clinical cases

authors： Zhao ZT,Li Y,Yuan HY,Ma FH,Song YM,Tian YT

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Lymphoepithelioma-like carcinomas (LELCs) are rare, malignant epithelial tumors, generally considered a subtype of squamous cell carcinoma. LELCs are undifferentiated and can occur in multiple tissues, although LELCs in the urinary tract are extremely rare. As such, evidence does not provide clinicians with ...

journal_title：World journal of clinical cases

authors： Lai SC,Seery S,Zhang W,Liu M,Zhang G,Wang JY

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Coronary intervention for bifurcation lesions is still challenging for interventional cardiologists. Left main (LM) bifurcation lesions have a higher risk due to the vast blood supply in this area and treatment choice is difficult. Ostial compromise of the side branch decreases patient prognosis, and its man...

journal_title：World journal of clinical cases

authors： Du BB,Tong YL,Wang XT,Liu GH,Liu K,Yang P,He YQ

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Pathological complete response (pCR) is rare in hormone receptor-positive (HR+) HER2-negative breast cancer (BC) treated with either endocrine therapy (ET) or chemotherapy. Radical resection of locoregional relapse, although potentially curative in some cases, is challenging when the tumor invades critical s...

journal_title：World journal of clinical cases

authors： Palleschi M,Maltoni R,Barzotti E,Melegari E,Curcio A,Cecconetto L,Sarti S,Manunta S,Rocca A

更新日期：2020-02-06 00:00:00

abstract：BACKGROUND:Pseudohypoparathyroidism type Ia (PHP Ia) is a rare hereditary syndrome, and patients with early PHP Ia are generally not diagnosed based on the presentation of cutaneous nodules as the main clinical feature. Here, we describe a Chinese boy with PHP Ia in whom the main clinical feature was cutaneous nodules,...

journal_title：World journal of clinical cases

authors： Li YL,Han T,Hong F

更新日期：2020-02-06 00:00:00

abstract：BACKGROUND:Unilateral exophthalmos is often caused by inflammation, neoplasm, infection, metabolic disease, vascular disorder and several other less common conditions. Reflex sympathetic dystrophy related to unilateral exophthalmos has not been reported in the past literature. CASE SUMMARY:We describe a 45-year-old fe...

journal_title：World journal of clinical cases

authors： Wu CM,Liao HE,Hsu SW,Lan SJ

更新日期：2020-01-26 00:00:00

abstract：BACKGROUND:Pancreatic cancer has a poor prognosis; 40%-50% of patients have liver metastases at the time of initial diagnosis and only 15%-20% undergo surgical resection. Irreversible electroporation (IRE) is a new, non-thermal local ablation method for solid tumors, which can induce cell membrane permeabilization, res...

journal_title：World journal of clinical cases

authors： Ma YY,Shi JJ,Chen JB,Xu KC,Niu LZ

更新日期：2020-01-26 00:00:00

abstract：BACKGROUND:Penetrating brain injury (PBI) is an uncommon emergency in neurosurgery, and transorbital PBI is a rare type of PBI. Reasonable surgical planning and careful postoperative management can improve the prognosis of patients. CASE SUMMARY:The first case is a 68-year-old male patient who was admitted to the hosp...

journal_title：World journal of clinical cases

authors： Xue H,Zhang WT,Wang GM,Shi L,Zhang YM,Yang HF

更新日期：2020-01-26 00:00:00

abstract：BACKGROUND:Distant metastasis, particularly visceral metastasis (VM), represents an important negative prognostic factor for prostate cancer (PCa) patients. However, due to the lower rate of occurrence of VM, studies on these patients are relatively rare. Consequently, studies focusing on prognostic factors associated ...

journal_title：World journal of clinical cases

authors： Cui PF,Cong XF,Gao F,Yin JX,Niu ZR,Zhao SC,Liu ZL

更新日期：2020-01-06 00:00:00